FluGen, founded in 2007, is the emerging leader in the fusion of intradermal delivery and vaccine biology.
The company has differentiating technologies that enable it to create value and compete in the large, rapidly growing influenza vaccine market.
FluGen is actively and aggressively advancing a valuable product pipeline that provides the company unique competitive advantages in this market and addresses significant unmet customer needs. These products include FluGen’s live attenuated vaccine candidate, REDEE FLU™ and a novel, vaccine-loaded intradermal delivery technology.
FluGen has assembled a matchless combination of business and scientific leadership that is focused on value creation through the successful execution of the company’s product development and commercialization plan.
There are an estimated 1 billion cases of seasonal influenza in the world every year which lead to 300,000 to 500,000 deaths. Groups most at risk of infection include healthcare workers, people with chronic diseases, pregnant women, young children and those over 65 years old.
While the highest rate of infection is among young children, the highest incidence of hospitalization and mortality is among the elderly. Seasonal influenza is the 7th leading cause of death in the U.S. and the leading cause of death in children ages 1-4 years.
Influenza virus outbreaks in humans can also be caused by the transmission of wholly avian influenza viruses to humans. One example is the current “Bird Flu” of the subtype H5N1 that infects avian species and occasionally also humans. It is highly pathogenic in humans but has not yet spread easily from human to human.
The Spanish Flu
The “Spanish Flu” virus of 1918 was an avian influenza virus of the H1N1 subtype which was directly or indirectly transmitted to humans. It infected over 50% of the world’s population which lead to over 40 million deaths. Notably, most of those killed were between the ages of 20-40. The disease spread around the globe in 2 months despite the relatively slow methods of transportation available at that time.